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Papers On Biology
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Modern Histological Technique and Safety
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This 5 page paper outlines procedures which may be used to create a safer working climate in the laboratory. A technique to substitute more risky materials is explored. Bibliography lists 3 sources.
Filename: SA049his.wps

Molecular Aspects of Latency in Herpes Simplex-1
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A 15 page sequel to KS-HSV.wps expanding on the more basic principles of that first paper. This paper focuses exclusively on HSV-1 and explores issues such as gene expression, gene products, function and possible mechanisms of action of the latency-associated gene expression in much greater depth. It also goes into more highly detailed discussion of molecular conditions and actions in the establishment of latency. Bibliography lists 10 sources.
Filename: KS-HSV-1.wps

Molecular Mixtures and Cross-Membrane Transport
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A 5 page review of “Drug Delivery: Breaching the Membrane”, an article by Joe Alper published in the May 3, 2002 edition of “Science”. Alper’s (2002) research concentrates on the cell membrane and the manner in which cross-membrane transport occurs, specifically the manner in which membrane-bound protein transporters function to allow various nutrients and hormones across. Alper’s paper adds insight to both the structure and function of the cell membrane and its components and how each relates to the molecular structure of the body’s complex mixture of chemicals. No additional sources are listed.
Filename: PPdrugTr.rtf

Molecular Modeling: Conformation Analysis and Energy Minimization
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A 6 page paper discussing these two aspects of computational chemistry. The next generation of narrowly-targeted drugs seems to be about to appear over the horizon. Conformation analysis and molecular modeling play increasing roles in new drug research. Conformation is important in that it can change according to its environment; energy levels affect action. Drug developers need to discover the most effective conformation, but they also need to be able to retain that conformation despite conditions external to the molecule. Bibliography lists 7 sources. Includes a Newman projection diagram.
Filename: KSmolecModel.rtf


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